哈佛医学院的15分SCI 涉嫌多处图片重复使用

前几天有网友爆料哈佛医学院的15分SCI (Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport)涉嫌多处图片重复使用,文章于2008年发表在Molecular Cell上,当前Molecular Cell的影响因子达到15.58。文章的其他信息如下:
doi: 10.1016/j.molcel.2007.12.024  issn: 1097-2765  pubmed: 18280241
Sang-Oh Yoon , Sejeong Shin  , Yuzhen Liu, Bryan A. Ballif , Michele S. Woo , Steven P. Gygi , John Blenis
Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.

网友Vernonia Abyssinica指出Figures 4E and 4F 存在惊人的相似之处,基本上可以说是一模一样,具体可以看下面的图片:

网友Fissurella Bridgesi指出其他图片也存在多处相同的地方,具体情况如下:

附录这篇文章的摘要:

The major participants of the Ras/ERK and PI3-kinase (PI3K) pathways are well characterized. The cellular response to activation of these pathways, however, can vary dramatically. How differences in signal strength, timing, spatial location, and cellular context promote specific cell-fate decisions remains unclear. Nuclear transport processes can have a major impact on the determination of cell fate; however, little is known regarding how nuclear transport is regulated by or regulates these pathways. Here we show that RSK and Akt, which are activated downstream of Ras/ERK and PI3K, respectively, modulate the Ran gradient and nuclear transport by interacting with, phosphorylating, and regulating Ran-binding protein 3 (RanBP3) function. Our findings highlight an important link between two major cell-fate determinants: nuclear transport and the Ras/ERK/RSK and PI3K/Akt signaling pathways.

不过上面这些情况放在国内是很容易摆平的,特别是大佬级别的人物,导致图片的重复使用无非就是粗心大意,疏忽导致的误用,或者原始记录丢失了,几句话之后就不会再有下文。

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