药厂防虫防鼠指南：虫害的调查和治理

虫害控制作为GMP的基本要求，是制药企业防止洁净室和药品污染的重要手段。ISPE在其《虫害控制手册》中给出了关于虫害监测结果的应用，即不同昆虫可能提示不同的环境控制状态，企业可以据此予以调查采取措施：Family (Species)监测到的昆虫Environmental Indicators环境状态提示Midge, Sciaridae, Gall midge, etc.摇蚊、蕈蚋、瘿蚊等Indicator of ease of entry into the building (flying)提示厂房内部易于进入（飞虫）Carabidae, Scutigeridae, Erythraeidae, etc.步甲，蚰蜒，赤螨等Indicator of ease of entry into the building (crawling)提示厂房内部易于进入（爬虫）Psychodidae, Drosophilidae, Phoridae, etc.蛾蠓，果蝇，蚤蝇Indicators of wastewater pollution提示存在废水污染Lachesillidae, Liposcelididae, Lathridiidae, etc.啮虫，书虱，薪甲Indicators of mold outbreak提示存在霉菌爆发可能Liposcelididae, Lepismatidae, Dermestidae, Acaridae, etc.书虱，衣鱼，皮蠹，螨Indicators of waste accumulation inside提示室内废弃物积累Araneae (Oecobiidae, Pholcidae, Salticidae, etc.蜘蛛类（拟壁钱科，幽灵蛛科，跳蛛科等）Indicators of insect populations提示存在大量昆虫Blattodea蟑螂Indicators of cleanliness levels提示洁净水平各类昆虫图片和介绍如下：Indicator of ease of entry into the building (flying)提示厂房内部易于进入（飞虫）Midge摇蚊

Sciaridae蕈蚋

Gall midge瘿蚊本身十分脆弱，飞翔能力不强，若厂房发现此类昆虫，说明昆虫易于进入，需要改善。

Indicator of ease of entry into the building (crawling)提示厂房内部易于进入（爬虫）Carabidae步甲

Scutigeridae蚰蜒

Erythraeidae赤螨

Indicators of wastewater pollution提示存在废水污染Psychodidae蛾蠓

Drosophilidae果蝇

Phoridae蚤蝇

Indicators of mold outbreak提示存在霉菌爆发可能Lachesillidae啮虫以真菌（包括霉菌）为食

Liposcelididae书虱体长约1mm或者更小，以霉菌为食

Lathridiidae薪甲

Indicators of waste accumulation inside提示室内废弃物积累Lepismatidae衣鱼

Dermestidae皮蠹

Acaridae螨

Indicators of insect populations提示存在大量昆虫Araneae蜘蛛以所有昆虫为食

Indicators of cleanliness levels提示洁净水平Blattodea蟑螂

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